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Effective Interventions

Core Elements and Fact Sheet 

About Sister to Sister  

Sister to Sister is a brief (20-minute), one-on-one, skill-based HIV/sexually transmitted disease (STD) risk-reduction behavioral intervention for sexually active African American women 18 to 45 years old that is delivered during the course of a routine medical visit.

The intervention is highly structured and implemented in a primary health care setting by nurses, health educators, or other professional clinic staff using a scripted teaching guide. It is educational, engaging, and gender-appropriate and uses videos, brainstorming, demonstrations, and skills-building activities. It is designed to be easily integrated into the health care provider’s standard clinical practice. As such, Sister to Sister is an effective tool for addressing the needs of both patients and providers in primary health care settings.

Intervention/Strategy Goals:

  1. Sister to Sister aims to provide intensive, culturally sensitive health information to empower and educate women in a clinical setting.
  2. Sister to Sister helps women understand the various behaviors that put them at risk for HIV and other STDs.
  3. Sister to Sister aims to enhance women’s knowledge, beliefs, motivation, confidence, and skills to help them make behavioral changes that will reduce their risk for STDs, especially HIV.

Intervention/Strategy Core Elements*:

Content core elements are the essential elements of what is being taught by the intervention that is believed to change risk behaviors.

  • Bolster outcome expectancies regarding condom use.
  • Teach, demonstrate, and practice negotiation and refusal skills. 
  • Condom use demonstration.
  • Build self-efficacy to empower the women to want to be safe sexually.
    Implementation core elements are the essential characteristics of the intervention that relate to the logistics that result in a positive learning environment.
  • Demonstrate a caring attitude and create a supportive environment.
  • Integrate and use the core intervention materials.
  • Implemented by a female health care provider who provides clinical services to women and has completed the 8-hour required training.
*Core elements are the characteristics of an individual intervention presumed to be responsible for the efficacy of the intervention.

Additional Information

Capacity Building Branch:    Phone: 404.718.7850    E-mail:
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