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Important CDC update on unsupported EBIs/strategies:

  • The CDC's strategy for High Impact HIV Prevention involves prioritizing and implementing an optimal combination of cost-effective, scalable interventions based on the current state of the science.  This shift should help improve the effectiveness of HIV prevention efforts, reduce HIV incidence, and ultimately increase the possibility of achieving an AIDS-free America.  In its ongoing effort to align HIV prevention resources with current surveillance data and this strategy, the Division of HIV/AIDS Prevention (DHAP) at CDC will not offer trainings or capacity building assistance on the following evidence-based interventions (EBIs): AIM, ¡Cuidate!, Focus on Youth, MIP, Nia, RAPP, Safety Counts, SHIELD, SIHLE, SISTA, Street Smart, RESPECT and VOICES/VOCES (except when used with MSM).  Some health departments or other funders may continue to support implementation of these EBIs, and the implementation materials for all these interventions will remain on this site and be available for download. If you have additional questions about this topic, please contact

    CDC's Division of Reproductive Health (DRH) will provide support to their grantees on AIM, ¡Cuidate!, and SIHLE. For further information on DRH's efforts, please contact Trisha Mueller at

    ETR Associates continues a body of work related to Focus on Youth. For further information, please contact Nancy Gonzalez-Caro at 1.800.325.3048 Ext. 237 and

New Advances in HIV Diagnostic Testing - Training for Health Professionals

An interactive e-Learning tool for clinicians to identify key characteristics and follow-up needs for patients with either positive or negative 4th generation HIV test results. CME/CNE available. Please visit

Added New High Impact HIV Prevention (HIP) Interventions & Strategies: 

Data to Care is a new public health strategy that aims to use HIV surveillance data to identify HIV-diagnosed individuals not in care, link them to care and support the HIV Care Continuum. Please visit the Data to Care homepage.

Social Network Strategy (SNS) for Counseling, Testing, and Referral (CTR) is an evidence supported approach to recruiting high-risk people. SNS is based on the underlying principles that people in the same social network share the same risks and risk behaviors for HIV. Please visit the SNS homepage

Ask, Screen, Intervene (ASI) is a course designed for care providers of persons living with HIV and promotes the use of the clinical encounter for the prevention of HIV/STD transmission. Please visit the ASI homepage

Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention

CDC's Prevention Research Synthesis (PRS) Project routinely updates an online Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention by adding newly identified evidence-based interventions (EBI) and best practices that have been scientifically proven to significantly reduce HIV risk or promote HIV care. The compendium comprises three chapters: a new chapter lists best practices for promoting linkage to, retention in and re-engagement in HIV medical care; a chapter lists EBIs for promoting HIV medication adherence among persons with HIV; and a chapter lists behavioral EBIs for reducing sex or drug injection behaviors directly impacting HIV transmission risk.

The materials on this site are designed for HIV/AIDS prevention with persons at risk for acquiring or transmitting HIV. They are meant to be resources used by HIV prevention providers such as health departments and community-based organizations so as to provide the best evidence-based HIV prevention services. These materials are not meant for the general public. They are not meant for children. They are not school-based HIV prevention strategies.

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