Effective Interventions

Effective Interventions

High Impact Prevention

Medication Adherence Strategies

Medication Adherence Banner Image

Table 1. Brief description of the 4 evidence-based HIV medication adherence strategies selected for translation into e-learning trainings for HIV providers.

Strategy Name Target population Description Duration
(Helping Enhance Adherence to Antiretroviral Therapy)
ART- naïve or changing ART regimen
Social support/problem-solving, individual/dyadic
intervention delivered before and in the first 2 months after initiation of ART. A patient-identified support partner is required to attend at least 2 of the first 4 sessions. The intervention includes problem-solving activities to identify and address barriers. This information is used to develop an individualized adherence plan (IAP) for patient. 
Five 1 1/2 to 2hr. sessions and 5 phone calls over 6 months
Partnership for Health - Medication Adherence 

ART-experienced  Brief (3-5 minute), clinic-based individual-level, provider-administered intervention emphasizing the importance of the patient-provider relationship to promote patient’s healthful behavior. The intervention includes adherence messages delivered to the patient during routine medical visits and the use of posters and brochures conveying the partnership theme and ART adherence messages. 3 to 5 minute session at each clinic visit
 Peer Support ART-experienced-or ART naïve Individual-and group-level intervention, where HIV-positive individuals, currently adherent to ART serve as peers, who provide medication-related social support through group meetings and weekly telephone calls to ART patients. Six twice-monthly 1-hour group meetings and weekly phone calls over 3 months 
SMART Couples
Sharing Medical Adherence Responsibilities Together
HIV-discordant couples, with poor medication adherence in the HIV-positive partner A couple-level intervention administered to discordant couples that addresses adherence to ART and safe sex behaviors within the couple dyad, fostering active support of both individuals.  Four 45-60 minute sessions over 5 weeks
* The first 2 sessions substitute as pre-medication and adherence counseling and are a routine part of HIV care. 

The 4 adherence strategies can be delivered by a variety of HIV providers, including medical providers, licensed social workers, HIV case managers, health educators and/or peers.

The materials on this site are designed for HIV/AIDS prevention with persons at risk for acquiring or transmitting HIV. They are meant to be resources used by HIV prevention providers such as health departments and community-based organizations so as to provide the best evidence-based HIV prevention services. These materials are not meant for the general public. They are not meant for children. They are not school-based HIV prevention strategies.